|
KMID : 1139120000010010125
|
|
Journal of Korea CHUNA Manual Medicine
2000 Volume.1 No. 1 p.125 ~ p.137
|
|
|
A preliminary study for the cerbral infarcted brain atrophy and osteoprosis via female reproductive physiology (Osteoporosis formation and alteration of female sex hormone after Cerebral Infarction)
|
|
Lee Jong-Soo
Yoon Sang-Hyub
|
|
|
Abstract
|
|
|
|
the aim of this study was to investigate whether osteoporosis can be advanced after cerebral infarction Of not and role of female sex hormone. all animals were classified 4 groups; group of ovariectomy (OVXgroup) group of cerebral infarction( INF group), group of combination ovariectomy and cerebral infarction(OVX + INF group), naturally intact group for control data (NOR group ). cerebral infarction was made by Chen,s method with some modification and ovariectomy was performed by Wayforth,s method. experimental data was collected at 15 days, 1 month, 3 months and 6months after starting observation. serum 17 was determined by radioimmunoassay, for comparision of osteoporosis formation, bone density, serum osteocalcin, Serum total calcium and phosphorus, Serum AST Concentration, Serum ALT Concentration, Creatinine Concentration were also calculated. we have found that cerebral ischemia decreases not only the serum concentration of 17 and inhibits but also the physiologically compensatory function of the ovariectomized rats and that the decreased estrogen concentration followed by cerebral infarction have not produced osteoporosis, regretfully.
|
|
|
KEYWORD
|
|
|
Osteoporosis, Cerebral Infarction, Female Sex Hormone
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|